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KMID : 0356919940270111686
Korean Journal of Anesthesiology
1994 Volume.27 No. 11 p.1686 ~ p.1691
Two Case Reports of Seizure Following Inadvertent Injection of Tranexamic Acid into Subarachnoid Space
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Abstract
We experienced two cases of convulsive seizure, accompanied with tachycardia and hypertension following spinal anesthesia for inguinal herniorrhaphy and skin graft.
Spinal anesthesia was performed with teracaine, 10% dextrose solution and epinephrine. Tranexamic acid was used instead of 10% dextrose solution inadvertently. About 2 hours after spinal anesthesia, the patients developed spastic rigidity at the
upper
extremities and chest wall that progressed to episthotonus and seizure preceded by tachycardia and hypertension.
About 40 hours after vigorous symptomatic treatment using mechanical ventilator, oxygen, short acting barbiturate, antihypertensive rugs and anticonvulsants, the patients had recovered completely with clear mental state. And they didn't show any
other
neurologic deficits except amnesia.
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